BI 2536
BI-2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM in a cell-free assay. BI-2536 inhibits Bromodomain 4 (BRD4) with Kd of 37 nM and potently suppresses c-Myc expression. BI-2536 induces apoptosis and attenuates autophagy. Phase 2.
| Trivial name | N/A |
| Catalog Number | S1109 |
| Molecular Formula | C7H8O |
| CAS# | 755038-02-9 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | CC1=CC=CC(=C1)O |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/BI-2536.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BI-2536-chemical-structure-S1109.gif |