Regorafenib

Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. Regorafenib induces autophagy.

Price Not Available 5mg Regorafenib Supplier Page
Trivial name Fluoro-Sorafenib, BAY 73-4506
Catalog Number S1178
Molecular Formula C21H15ClF4N4O3
CAS# 755037-03-7
Inchi InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)
Inchi Key FNHKPVJBJVTLMP-UHFFFAOYSA-N
SMILES CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F
Size 5mg
Supplier Page http://www.selleckchem.com/products/BAY-73-4506.html
Additional Information https://file.selleck.cn/downloads/struct/BAY-73-4506-chemical-structure-s1178.gif