Lovastatin
Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, used for lowering cholesterol (hypolipidemic agent). Lovastatin triggers autophagy.
| Trivial name | Mevinolin, MK-803 |
| Catalog Number | S2061 |
| Molecular Formula | C21H23N7O3S |
| CAS# | 75330-75-5 |
| Inchi | InChI=1S/C21H23N7O3S/c1-27-9-11-28(12-10-27)32(30,31)17-6-4-15(5-7-17)18-14-24-20(22)19(26-18)21(29)25-16-3-2-8-23-13-16/h2-8,13-14H,9-12H2,1H3,(H2,22,24)(H,25,29) |
| Inchi Key | FHCSBLWRGCOVPT-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C3=CN=C(C(=N3)C(=O)NC4=CN=CC=C4)N |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/lovastatin-mevacor.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s2061-lovastatin-mk-803-chemical-structure.png |