GS-6201
GS-6201 (CVT-6883) is a selective adenosine A2B receptor antagonist. GS-6201 displays high affinity and selectivity for the human adenosine A2B receptors (Ki=22 nM). GS-6201 reduces caspase-1 activity in the heart, and attenuates cardiac remodeling after acute myocardial infarction (AMI) in the mouse. GS-62013 attenuates the airway reactivity induced by NECA, AMP, or allergen in sensitized mice.
| Trivial name | CVT-6883 |
| Catalog Number | E7723 |
| Molecular Formula | C16H16ClNO3 |
| CAS# | 752222-83-6 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | OC1=CC=C(C=C1)C2CNCCC3=C(Cl)C(=C(O)C=C23)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/gs-6201.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7723-gs-6201-chemical-structure-tube.png |