Itanapraced (CHF 5074)
Itanapraced (CHF 5074, CSP-1103) is a gamma-secretase modulator that reduces Aβ42 and Aβ40 secretion. The IC50s of CHF5074 for inhibition of COX-1 and COX-2 is above 100 μmol/L.
| Trivial name | CSP-1103 |
| Catalog Number | S7323 |
| Molecular Formula | C16H11Cl2FO2 |
| CAS# | 749269-83-8 |
| Inchi | InChI=1S/C16H11Cl2FO2/c17-12-4-1-9(7-13(12)18)11-3-2-10(8-14(11)19)16(5-6-16)15(20)21/h1-4,7-8H,5-6H2,(H,20,21) |
| Inchi Key | LIYLTQQDABRNRX-UHFFFAOYSA-N |
| SMILES | C1CC1(C2=CC(=C(C=C2)C3=CC(=C(C=C3)Cl)Cl)F)C(=O)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/chf-5074.html |
| Additional Information | https://file.selleck.cn/downloads/struct/chf-5074-chemical-structure-s7323.gif |