Ciglitazone
Ciglitazone is a potent and selective PPARγ agonist (EC50=3 μM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells.
| Trivial name | ADD-3878, U-63287 |
| Catalog Number | E7168 |
| Molecular Formula | C18H24O2 |
| CAS# | 74772-77-3 |
| Inchi | InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1 |
| Inchi Key | VOXZDWNPVJITMN-ZBRFXRBCSA-N |
| SMILES | CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ciglitazone.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7168-ciglitazone-chemical-structure-tube.png |