Disodium Methotrexate

An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.

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Catalog Number API7413345
Alternative Name(s) Methotrexate disodium salt METHOTREXATE SODIUM methotrexate disodium Sodium methotrexate
Research Area Anti-Tumor APIs
Molecular Formula C20H20N8Na2O5
CAS# 7413-34-5
SMILES CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]
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