Dolichol-22 is a lipid molecule that functions in the biosynthesis of fatty acids. It is found in the liver cells and other tissues, where it is involved in the metabolism of cholesterol. Dolichol-22 is also an endogenous precursor of dolichyl phosphate, which is used as a cofactor for enzymes that catalyze reactions involving glycosylation. In vivo treatment with Dolichol-22 has been shown to increase insulin sensitivity and reduce plasma glucose levels in Sprague-Dawley rats and to provide anti-aging effects by increasing the lifespan of cultured human liver cells.