Givinostat (ITF2357)
Givinostat (ITF2357) is a potent HDAC inhibitor for maize HD2, HD1B and HD1A with IC50 of 10 nM, 7.5 nM and 16 nM in cell-free assays. Phase 2.
| Trivial name | N/A |
| Catalog Number | S2170 |
| Molecular Formula | C24H27N3O4.HCl.H2O |
| CAS# | 732302-99-7 |
| Inchi | InChI=1S/C24H27N3O4.ClH.H2O/c1-3-27(4-2)15-17-5-7-21-14-18(6-8-20(21)13-17)16-31-24(29)25-22-11-9-19(10-12-22)23(28)26-30;;/h5-14,30H,3-4,15-16H2,1-2H3,(H,25,29)(H,26,28);1H;1H2 |
| Inchi Key | FKGKZBBDJSKCIS-UHFFFAOYSA-N |
| SMILES | CCN(CC)CC1=CC2=C(C=C1)C=C(C=C2)COC(=O)NC3=CC=C(C=C3)C(=O)NO.O.Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/ITF2357(Givinostat).html |
| Additional Information | https://file.selleck.cn/downloads/struct/ITF2357-Givinostat-chemical-structure-S2170.gif |