OSI-930
OSI-930 is a potent inhibitor of Kit (c-Kit), KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively; also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl. Phase 1.
| Trivial name | N/A |
| Catalog Number | S1220 |
| Molecular Formula | C20H25F3N6O3 |
| CAS# | 728033-96-3 |
| Inchi | InChI=1S/C20H25F3N6O3/c21-20(22,23)32-17-4-2-1-3-15(17)11-26-19-27-12-16(29(30)31)18(28-19)25-10-14-7-5-13(9-24)6-8-14/h1-4,12-14H,5-11,24H2,(H2,25,26,27,28) |
| Inchi Key | HKOWATVSFKRXRW-UHFFFAOYSA-N |
| SMILES | C1CC(CCC1CN)CNC2=NC(=NC=C2[N+](=O)[O-])NCC3=CC=CC=C3OC(F)(F)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/OSI-930.html |
| Additional Information | https://file.selleck.cn/downloads/struct/OSI-930-chemical-structure-S1220.gif |