OSI-930
OSI-930 is a potent inhibitor of Kit (c-Kit), KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively; also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl. Phase 1.
| Trivial name | N/A |
| Catalog Number | S1220 |
| Molecular Formula | C22H16F3N3O2S |
| CAS# | 728033-96-3 |
| Inchi | InChI=1S/C22H16F3N3O2S/c23-22(24,25)30-16-7-5-15(6-8-16)28-21(29)20-19(10-12-31-20)27-13-14-9-11-26-18-4-2-1-3-17(14)18/h1-12,27H,13H2,(H,28,29) |
| Inchi Key | FGTCROZDHDSNIO-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/OSI-930.html |
| Additional Information | https://file.selleck.cn/downloads/struct/OSI-930-chemical-structure-S1220.gif |