Barasertib (AZD1152-HQPA)
Defosbarasertib (AZD1152-HQPA, AZD2811, INH-34, Barasertib-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, ~3700 fold more selective for Aurora B over Aurora A. Phase 1.
Trivial name | AZD2811, INH-34, Barasertib-HQPA , Defosbarasertib |
Catalog Number | S1147 |
Molecular Formula | C26H30FN7O3 |
CAS# | 722544-51-6 |
Inchi | InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,3 2,33) |
Inchi Key | QYZOGCMHVIGURT-UHFFFAOYSA-N |
SMILES | CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCO |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/AZD1152-HQPA.html |
Additional Information | https://file.selleck.cn/downloads/struct/AZD1152-HQPA-chemical-structure-S1147.gif |