PHA-793887
PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM. It is greater than 6-fold more selective for CDK2, 5, and 7 than CDK1, 4, and 9. PHA-793887 induces cell-cycle arrest and apoptosis. Phase 1.
| Trivial name | N/A |
| Catalog Number | S1487 |
| Molecular Formula | C12H8N2 |
| CAS# | 718630-59-2 |
| Inchi | InChI=1S/C12H8N2/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1/h1-8H |
| Inchi Key | DGEZNRSVGBDHLK-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/PHA-793887.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PHA-793887-chemical-structure-S1487.gif |