PHA-793887
PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM. It is greater than 6-fold more selective for CDK2, 5, and 7 than CDK1, 4, and 9. PHA-793887 induces cell-cycle arrest and apoptosis. Phase 1.
| Trivial name | N/A |
| Catalog Number | S1487 |
| Molecular Formula | C19H31N5O2 |
| CAS# | 718630-59-2 |
| Inchi | InChI=1S/C19H31N5O2/c1-12(2)10-15(25)20-17-14-11-24(19(3,4)16(14)21-22-17)18(26)13-6-8-23(5)9-7-13/h12-13H,6-11H2,1-5H3,(H2,20,21,22,25) |
| Inchi Key | HUXYBQXJVXOMKX-UHFFFAOYSA-N |
| SMILES | CC(C)CC(=O)NC1=NNC2=C1CN(C2(C)C)C(=O)C3CCN(CC3)C |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/PHA-793887.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PHA-793887-chemical-structure-S1487.gif |