PF-562271
PF-562271 (PF-00562271) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
Trivial name | PF-00562271 |
Catalog Number | S2890 |
Molecular Formula | C14H20N6O5S |
CAS# | 717907-75-0 |
SMILES | NC(CCSCC1OC(C(O)C1O)[N]2C=NC3=C2N=CN=C3N)C(O)=O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/pf-562271.html |
Additional Information | https://file.selleck.cn/downloads/struct/PF-562271-chemical-structure-s2890.jpg |