AC480 (BMS-599626)

AC480 (BMS-599626) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, ~8-fold less potent to HER4, >100-fold to VEGFR2, c-Kit, Lck, MET etc. Phase 1.

Price Not Available 5mg AC480 (BMS-599626) Supplier Page

Trivial name	N/A
Catalog Number	S1056
Molecular Formula	C27H27FN8O3
CAS#	714971-09-2
Inchi	InChI=1S/C27H27FN8O3/c1-17-23(34-27(37)39-15-22-14-38-8-7-29-22)13-36-25(17)26(30-16-32-36)33-21-5-6-24-19(10-21)11-31-35(24)12-18-3-2-4-20(28)9-18/h2-6,9-11,13,16,22,29H,7-8,12,14-15H2,1H3,(H,34,37)( H,30,32,33)/t22-/m0/s1
Inchi Key	LUJZZYWHBDHDQX-QFIPXVFZSA-N
SMILES	CC1=C2C(=NC=NN2C=C1NC(=O)OCC3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6)F
Size	5mg
Supplier Page	http://www.selleckchem.com/products/BMS-599626.html
Additional Information	https://file.selleck.cn/downloads/struct/bms-599626-ac480-chemical-structure-s1056.gif