Plinabulin
Plinabulin is a vascular disrupting agent (VDA) against tubulin-depolymerizing with IC50 of 9.8~18 nM in tumor cells. Phase 1/2.
| Trivial name | NPI-2358 |
| Catalog Number | S1176 |
| Molecular Formula | C19H20N4O2 |
| CAS# | 714272-27-2 |
| Inchi | InChI=1S/C19H20N4O2/c1-19(2,3)16-13(20-11-21-16)10-15-18(25)22-14(17(24)23-15)9-12-7-5-4-6-8-12/h4-11H,1-3H3,(H,20,21)(H,22,25)(H,23,24)/b14-9-,15-10- |
| Inchi Key | UNRCMCRRFYFGFX-TYPNBTCFSA-N |
| SMILES | CC(C)(C)C1=C(N=CN1)C=C2C(=O)NC(=CC3=CC=CC=C3)C(=O)N2 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/NPI-2358.html |
| Additional Information | https://file.selleck.cn/downloads/struct/NPI2358-Plinabulin-chemical-structure-S1176.gif |