Saxagliptin hydrochloride

Saxagliptin hydrochloride (BMS-477118 hydrochloride) is a potent, selective, reversible, competitive, and orally active inhibitor of dipeptidyl peptidase-4 (DPP-4). It exhibits 400-950 fold selective inhibition of DPP-4 than DPP-8. Saxagliptin hydrochloride is used in the research of type 2 diabetes mellitus research.

Trivial name BMS-477118 hydrochloride
Catalog Number E6005
Molecular Formula C45H74O11
CAS# 709031-78-7
Inchi InChI=1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18 ,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13-,17-15-,21-18+/t25-,26-,27+,28+,29?,30-,31-,32-,33-,34-,35-,36-,38+,40+,41+,42-,44+,45-/m0/s1
Inchi Key MNULEGDCPYONBU-WFTQPAASSA-N
SMILES CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C
Size 1g
Supplier Page http://www.selleckchem.com/products/saxagliptin-hydrochloride.html
Additional Information https://file.selleck.cn/downloads/struct/E6005-Saxagliptin-hydrochloride-chemical-structure.png