Mitoxantrone 2HCl
Mitoxantrone 2HCl is a dihydrochloride salt of Mitoxantrone. Mitoxantrone is an inhibitor of type II topoisomerase and protein kinase C (PKC) with IC50 of 8.5 μM for PKC. Mitoxantrone inhibits cell proliferative growth of MCF-7/wt cells with IC50 of 0.42 μM. Mitoxantrone also induces apoptosis.
Trivial name | NSC-301739 2HCl, Mitozantrone 2HCl |
Catalog Number | S2485 |
Molecular Formula | C18H13BrN4O |
CAS# | 70476-82-3 |
Inchi | InChI=1S/C18H13BrN4O/c1-2-4-17(24)22-14-7-8-16-15(10-14)18(21-11-20-16)23-13-6-3-5-12(19)9-13/h3,5-11H,1H3,(H,22,24)(H,20,21,23) |
Inchi Key | BTYYWOYVBXILOJ-UHFFFAOYSA-N |
SMILES | CC#CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/Mitoxantrone-Hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/Mitoxantrone-Hydrochloride-chemical-structure-S1889.gif |