Mitoxantrone 2HCl
Mitoxantrone 2HCl is a dihydrochloride salt of Mitoxantrone. Mitoxantrone is an inhibitor of type II topoisomerase and protein kinase C (PKC) with IC50 of 8.5 μM for PKC. Mitoxantrone inhibits cell proliferative growth of MCF-7/wt cells with IC50 of 0.42 μM. Mitoxantrone also induces apoptosis.
Trivial name | NSC-301739 2HCl, Mitozantrone 2HCl |
Catalog Number | S2485 |
Molecular Formula | C22H29ClN4O6.2HCl |
CAS# | 70476-82-3 |
Inchi | InChI=1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H |
Inchi Key | ZAHQPTJLOCWVPG-UHFFFAOYSA-N |
SMILES | C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/Mitoxantrone-Hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/Mitoxantrone-Hydrochloride-chemical-structure-S1889.gif |