BX-912
BX912 is a potent and specific PDK1 inhibitor with IC50 of 12 nM, 9- and 105- fold greater selectivity for PDK1 than PKA and PKC in cell-free assays, respectively. In comparison to GSK3β, selectivity for PDK1 is 600-fold.
| Trivial name | N/A |
| Catalog Number | S1275 |
| Molecular Formula | C20H23BrN8O |
| CAS# | 702674-56-4 |
| Inchi | InChI=1S/C20H23BrN8O/c21-17-12-24-19(28-18(17)23-7-6-16-11-22-13-25-16)26-14-4-3-5-15(10-14)27-20(30)29-8-1-2-9-29/h3-5,10-13H,1-2,6-9H2,(H,22,25)(H,27,30)(H2,23,24,26,28) |
| Inchi Key | DMMILYKXNCVKOJ-UHFFFAOYSA-N |
| SMILES | C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCC4=CN=CN4)Br |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/bx-912.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BX-912-chemical-structure-s1275.gif |