Galunisertib (LY2157299)
Galunisertib (LY2157299) is a potent TGFβ receptor I (TβRI) inhibitor with IC50 of 56 nM in a cell-free assay. Phase 2/3.
Trivial name | N/A |
Catalog Number | S2230 |
Molecular Formula | C22H19N5O |
CAS# | 700874-72-2 |
Inchi | InChI=1S/C22H19N5O/c1-13-4-2-5-18(25-13)21-20(19-6-3-11-27(19)26-21)15-9-10-24-17-8-7-14(22(23)28)12-16(15)17/h2,4-5,7-10,12H,3,6,11H2,1H3,(H2,23,28) |
Inchi Key | IVRXNBXKWIJUQB-UHFFFAOYSA-N |
SMILES | CC1=NC(=CC=C1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/ly2157299.html |
Additional Information | https://file.selleck.cn/downloads/struct/LY2157299-chemical-structure-S2230.gif |