NSC 66811

Cell-permeable. Potent MDM2 (murine double minute 2) inhibitor (Ki = 120 nM) that disrupts MDM2-p53 interaction and activates p53 in cancer cells. Induces p21, p53 and MDM2 accumulation in human colon cancer cells in vitro.

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Catalog Number	ABU-004
Alternative Name(s)	2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol
CAS#	6964-62-1
Inchi	InChI=1S/C23H20N2O/c1-16-12-13-18-14-15-20(23(26)22(18)24-16)21(17-8-4-2-5-9-17)25-19-10-6-3-7-11-19/h2-15,21,25-26H,1H3
Inchi Key	WEENRMPCSWFMTE-UHFFFAOYSA-N
SMILES	CC1=NC2=C(C=C1)C=CC(=C2O)C(C3=CC=CC=C3)NC4=CC=CC=C4
Size	Inquiry
Supplier Page	https://www.agingclocks.com/nsc-66811-item-1543.html