ZM 306416
ZM 306416 (CB 676475) is a VEGFR (Flt and KDR) inhibitor for VEGFR1 with IC50 of 0.33 μM, but also found to inhibit EGFR with IC50 of <10 nM.
| Trivial name | CB 676475 |
| Catalog Number | S2897 |
| Molecular Formula | C16H13ClFN3O2 |
| CAS# | 690206-97-4 |
| Inchi | InChI=1S/C16H13ClFN3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-12-4-3-9(17)5-11(12)18/h3-8H,1-2H3,(H,19,20,21) |
| Inchi Key | YHUIUSRCUKUUQA-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/zm-306416.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ZM-306416-chemical-structure-s2897.jpg |