IWP-2
IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses. IWP-2 specifically inhibits CK1δ.
| Trivial name | N/A |
| Catalog Number | S7085 |
| Molecular Formula | C22H18N4O2S3 |
| CAS# | 686770-61-6 |
| Inchi | InChI=1S/C22H18N4O2S3/c1-13-7-8-15-17(11-13)31-21(23-15)25-18(27)12-30-22-24-16-9-10-29-19(16)20(28)26(22)14-5-3-2-4-6-14/h2-8,11H,9-10,12H2,1H3,(H,23,25,27) |
| Inchi Key | WRKPZSMRWPJJDH-UHFFFAOYSA-N |
| SMILES | CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/iwp-2.html |
| Additional Information | https://file.selleck.cn/downloads/struct/IWP-2-chemical-structure-s7085.gif |