4-Hydroxytamoxifen (Afimoxifene)
4-Hydroxytamoxifen (Afimoxifene) is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer. It activates on-target modification frequency for intein-Cas9 variants.
Trivial name | Afimoxifene |
Catalog Number | S7827 |
Molecular Formula | C26H29NO2 |
CAS# | 68392-35-8 |
Inchi | InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3 |
Inchi Key | TXUZVZSFRXZGTL-UHFFFAOYSA-N |
SMILES | CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3 |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/4-hydroxytamoxifen-4-ht-afimoxifene.html |
Additional Information | https://file.selleck.cn/downloads/struct/s7827-4-hydroxytamoxifen-afimoxifene-chemical-structure.png |