4-Hydroxytamoxifen (Afimoxifene)

4-Hydroxytamoxifen (Afimoxifene) is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer. It activates on-target modification frequency for intein-Cas9 variants.

Trivial name Afimoxifene
Catalog Number S7827
Molecular Formula C26H29NO2
CAS# 68392-35-8
Inchi InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3
Inchi Key TXUZVZSFRXZGTL-UHFFFAOYSA-N
SMILES CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
Size 1g
Supplier Page http://www.selleckchem.com/products/4-hydroxytamoxifen-4-ht-afimoxifene.html
Additional Information https://file.selleck.cn/downloads/struct/s7827-4-hydroxytamoxifen-afimoxifene-chemical-structure.png