Tivozanib hydrate | MedChemExpress (MCE)

Tivozanib hydrate (AV-951 hydrate; KRN951 hydrate) is the hydrate form of Tivozanib (HY-10977). Tivozanib hydrate is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2 3, with IC50s of 30, 6.5 and 15 nM, respectively. Tivozanib hydrate exhibits antitumor efficacy[1].

Trivial name Tivozanib hydrate
Catalog Number HY-112467
Alternative Name(s) AV-951 hydrate; KRN951 hydrate
Research Area Cancer
CAS# 682745-40-0
Purity ≥98.0%
SMILES O=C(NC1=CC=C(C=C1Cl)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC4=NOC(C)=C4.O
Size 1 mg
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