SPDP
SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with cysteine sulfhydryls. SPDP is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).
| Trivial name | SPDP Crosslinker |
| Catalog Number | S0564 |
| Molecular Formula | C12H12N2O4S2 |
| CAS# | 68181-17-9 |
| SMILES | C1CC(=O)N(C1=O)OC(=O)CCSSC2=CC=CC=N2 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/spdp.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s0564-spdp-chemical-structure.png |