CBR-5884
CBR-5884 is a selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and was selectively toxic to cancer cell lines with high serine biosynthetic activity.
Trivial name | N/A |
Catalog Number | S9645 |
Molecular Formula | C14H12N2O4S2 |
CAS# | 681159-27-3 |
SMILES | CCOC(=O)C1=C(C(=C(S1)NC(=O)C2=CC=CO2)SC#N)C |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/cbr-5884.html |
Additional Information | https://file.selleck.cn/downloads/struct/s9645-cbr-5884-chemical-structure.gif |