PIN1 inhibitor API-1
PIN1 inhibitor API-1 is a specific Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) inhibitor with IC50 of 72.3 nM. PIN1 inhibitor API-1 targets Pin1 peptidyl-prolyl isomerase domain and inhibits Pin1 cis-trans isomerizing activity. PIN1 inhibitor API-1 up-regulates miRNA biogenesis by retaining active XPO5 conformation and suppresses HCC development.
Trivial name | N/A |
Catalog Number | S6893 |
Molecular Formula | C15H13F3N6O2 |
CAS# | 680622-70-2 |
SMILES | NC1=NC2=NC=NC2=C([NH]1)OCC3=CC=C(CNC(=O)C(F)(F)F)C=C3 |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/pin1-inhibitor-api-1.html |
Additional Information | https://file.selleck.cn/downloads/struct/s6893-api-1-chemical-structure.gif |