Thapsigargin
Thapsigargin is a potent, non-competitive inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) with IC50 of 0.353 nM or 0.448 nM for the carbachol-evoked [Ca2+]i-transients with or without a KCl-prestimulation. Thapsigargin induces cell apoptosis. Thapsigargin is extracted from a plant, Thapsia garganica.
| Trivial name | N/A |
| Catalog Number | S7895 |
| Molecular Formula | C34H50O12 |
| CAS# | 67526-95-8 |
| SMILES | CCCCCCCC(=O)OC1C2C(=C(C1OC(=O)C(=CC)C)C)C3C(C(CC2(C)OC(=O)C)OC(=O)CCC)(C(C(=O)O3)(C)O)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/thapsigargin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s7895-thapsigargin-chemical-structure.gif |