Linagliptin (GSK2118436)

Linagliptin (GSK2118436) is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM and exhibits a 10,000-fold higher selectivity for DPP-4 than for other dipeptidyl peptidases such as DPP-2, DPP-8, and DPP-9. Linagliptin activates glomerular autophagy in a model of type 2 diabetes. DPP4 mediates ferroptosis in TP53-deficient CRC cells.

Price Not Available 100mg Linagliptin (GSK2118436) Supplier Page

Trivial name	BI-1356
Catalog Number	S3031
Molecular Formula	C25H28N8O2
CAS#	668270-12-0
Inchi	InChI=1S/C25H28N8O2/c1-4-5-13-32-21-22(29-24(32)31-12-8-9-17(26)14-31)30(3)25(35)33(23(21)34)15-20-27-16(2)18-10-6-7-11-19(18)28-20/h6-7,10-11,17H,8-9,12-15,26H2,1-3H3/t17-/m1/s1
Inchi Key	LTXREWYXXSTFRX-QGZVFWFLSA-N
SMILES	CC#CCN1C2=C(N=C1N3CCCC(C3)N)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C
Size	100mg
Supplier Page	http://www.selleckchem.com/products/linagliptin-bi-1356.html
Additional Information	https://file.selleck.cn/downloads/struct/Linagliptin-chemical-structure-s3031.gif