E-64
E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. E-64 induces oxidative stress and apoptosis in Filarial Parasite.
| Trivial name | N/A |
| Catalog Number | S7379 |
| Molecular Formula | C15H27N5O5 |
| CAS# | 66701-25-5 |
| Inchi | InChI=1S/C15H27N5O5/c1-8(2)7-9(20-13(22)10-11(25-10)14(23)24)12(21)18-5-3-4-6-19-15(16)17/h8-11H,3-7H2,1-2H3,(H,18,21)(H,20,22)(H,23,24)(H4,16,17,19)/t9-,10+,11+/m0/s1 |
| Inchi Key | LTLYEAJONXGNFG-HBNTYKKESA-N |
| SMILES | CC(C)CC(C(=O)NCCCCN=C(N)N)NC(=O)C1C(O1)C(=O)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/e-64.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E-64-chemical-structure-s7379.gif |