Mizagliflozin (KWA 0711)

Mizagliflozin (KWA 0711) is a novel, potent, selective sodium glucose co-transporter 1 (SGLT1) inhibitor with Ki of 27 nM for human SGLT1. The selectivity ratio (Ki value for human SGLT2/Ki value for human SGLT1) of mizagliflozin is 303. Mizagliflozin shows the potential use for the amelioration of chronic constipation.

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Trivial name	N/A
Catalog Number	S8939
Molecular Formula	C28H44N4O8
CAS#	666843-10-3
Inchi	InChI=1S/C28H44N4O8/c1-15(2)21-19(25(32-31-21)40-26-24(36)23(35)22(34)20(13-33)39-26)12-17-7-8-18(11-16(17)3)38-10-6-9-30-14-28(4,5)27(29)37/h7-8,11,15,20,22-24,26,30,33-36H,6,9-10,12-14H2,1-5H3,(H2,2 9,37)(H,31,32)/t20-,22-,23+,24-,26+/m1/s1
Inchi Key	LREHMKLEOJAVMQ-TXKDOCKMSA-N
SMILES	CC1=C(C=CC(=C1)OCCCNCC(C)(C)C(=O)N)CC2=C(NN=C2OC3C(C(C(C(O3)CO)O)O)O)C(C)C
Size	5mg
Supplier Page	http://www.selleckchem.com/products/mizagliflozin.html
Additional Information	https://file.selleck.cn/downloads/struct/mizagliflozin-chemical-structure-s8939.gif