2-Acetylphenothiazine (ML171)

2-Acetylphenothiazine (ML171, 2-APT) is a potent and selective inhibitor of NADPH-oxidase with IC50s of 0.25 μM, 5 μM, 3μM, 5 μM and 5.5 μM for NOX1, NOX2, NOX3, NOX4 and xanthine oxidase, respectively.

Trivial name 2-APT
Catalog Number S5304
Molecular Formula C14H11NOS
CAS# 6631-94-3
Inchi InChI=1S/C14H11NOS/c1-9(16)10-6-7-14-12(8-10)15-11-4-2-3-5-13(11)17-14/h2-8,15H,1H3
Inchi Key JWGBOHJGWOPYCL-UHFFFAOYSA-N
SMILES CC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2
Size 25mg
Supplier Page http://www.selleckchem.com/products/2-acetylphenothiazine-ml171.html
Additional Information https://file.selleck.cn/downloads/struct/2-acetylphenothiazine-chemical-structure-s5304.gif