2-Acetylphenothiazine (ML171)

2-Acetylphenothiazine (ML171, 2-APT) is a potent and selective inhibitor of NADPH-oxidase with IC50s of 0.25 μM, 5 μM, 3μM, 5 μM and 5.5 μM for NOX1, NOX2, NOX3, NOX4 and xanthine oxidase, respectively.

Trivial name 2-APT
Catalog Number S5304
Molecular Formula C27H45NO3
CAS# 6631-94-3
Inchi InChI=1S/C27H45NO3/c1-15-4-7-25-27(3,31)21-6-5-17-18(20(21)14-28(25)13-15)11-22-19(17)12-24(30)23-10-16(29)8-9-26(22,23)2/h15-25,29-31H,4-14H2,1-3H3/t15-,16-,17+,18+,19-,20-,21-,22-,23+,24-,25-,26+,27 -/m0/s1
Inchi Key IUKLSMSEHKDIIP-BZMYINFQSA-N
SMILES CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)(C)O
Size 25mg
Supplier Page http://www.selleckchem.com/products/2-acetylphenothiazine-ml171.html
Additional Information https://file.selleck.cn/downloads/struct/2-acetylphenothiazine-chemical-structure-s5304.gif