AMG-517
AMG 517 is a potent and selective TRPV1 antagonist, and antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM， respectively.
| Trivial name | N/A |
| Catalog Number | S7115 |
| Molecular Formula | C20H13F3N4O2S |
| CAS# | 659730-32-2 |
| Inchi | InChI=1S/C20H13F3N4O2S/c1-11(28)26-19-27-18-15(3-2-4-16(18)30-19)29-17-9-14(24-10-25-17)12-5-7-13(8-6-12)20(21,22)23/h2-10H,1H3,(H,26,27,28) |
| Inchi Key | YUTIXVXZQIQWGY-UHFFFAOYSA-N |
| SMILES | CC(=O)NC1=NC2=C(C=CC=C2S1)OC3=NC=NC(=C3)C4=CC=C(C=C4)C(F)(F)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/amg-517.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AMG-517-chemical-structure-s7115.gif |