SU11274
SU11274 (PKI-SU11274) is a selective Met (c-Met) inhibitor with IC50 of 10 nM in cell-free assays, no effects on PGDFRβ, EGFR or Tie2. SU11274 induces autophagy, apoptosis and cell cycle arrest.
| Trivial name | PKI-SU11274 |
| Catalog Number | S1080 |
| Molecular Formula | C11H12N2O2 |
| CAS# | 658084-23-2 |
| Inchi | InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m1/s1 |
| Inchi Key | QIVBCDIJIAJPQS-SECBINFHSA-N |
| SMILES | C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/SU11274.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SU11274-chemical-structure-S1080.gif |