SU11274
SU11274 (PKI-SU11274) is a selective Met (c-Met) inhibitor with IC50 of 10 nM in cell-free assays, no effects on PGDFRβ, EGFR or Tie2. SU11274 induces autophagy, apoptosis and cell cycle arrest.
| Trivial name | PKI-SU11274 |
| Catalog Number | S1080 |
| Molecular Formula | C28H30CIN5O4S |
| CAS# | 658084-23-2 |
| Inchi | InChI=1S/C28H30ClN5O4S/c1-17-25(30-18(2)26(17)28(36)34-12-10-32(3)11-13-34)16-23-22-15-21(8-9-24(22)31-27(23)35)39(37,38)33(4)20-7-5-6-19(29)14-20/h5-9,14-16,30H,10-13H2,1-4H3,(H,31,35)/b23-16- |
| Inchi Key | FPYJSJDOHRDAMT-KQWNVCNZSA-N |
| SMILES | CC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)C=C3C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/SU11274.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SU11274-chemical-structure-S1080.gif |