Metformin
Metformin (1,1-Dimethylbiguanide), a widely used drug for treatment of type 2 diabetes, activates AMP-activated protein kinase (AMPK) in hepatocytes. Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153.
| Trivial name | 1,1-Dimethylbiguanide |
| Catalog Number | S5958 |
| Molecular Formula | C4H11N5 |
| CAS# | 657-24-9 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | CN(C)C(=N)NC(N)=N |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/metformin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s5958-metformin-chemical-structure.gif |