AG-1024
AG-1024 (Tyrphostin, AGS 200) inhibits IGF-1R autophosphorylation with IC50 of 7 μM, is less potent to IR with IC50 of 57 μM and specifically distinguishes between InsR and IGF-1R (as compared to other tyrphostins).
| Trivial name | Tyrphostin, AGS 200 |
| Catalog Number | S1234 |
| Molecular Formula | C14H13BrN2O |
| CAS# | 65678-07-1 |
| Inchi | InChI=1S/C14H13BrN2O/c1-14(2,3)11-5-9(4-10(7-16)8-17)6-12(15)13(11)18/h4-6,18H,1-3H3 |
| Inchi Key | ABBADGFSRBWENF-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C1=C(C(=CC(=C1)C=C(C#N)C#N)Br)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ag-1024-tyrphostin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AG-1024-chemical-structure-s1234.gif |