Bestatin hydrochloride
Bestatin hydrochloride is an inhibitor of aminopeptidase N and enkephalinase that elevates the levels of angiotensin II and angiotensin III. It also acts as a non-competitive inhibitor (α > 1) of porcine DPP-IV with a Ki value of 75 μM. It reduces DPP-IV activity, decreases cell viability, and increases DNA fragmentation in vitro. It has the potential to treat skin conditions like acne, psoriasis and keloids.
Catalog Number | E4916 |
Molecular Formula | C18H17N3O4S |
CAS# | 65391-42-6 |
Inchi | InChI=1S/C18H17N3O4S/c1-25-15-8-10-16(11-9-15)26(23,24)21-17-3-2-12-19-18(17)20-13-4-6-14(22)7-5-13/h2-12,21-22H,1H3,(H,19,20) |
Inchi Key | URCVCIZFVQDVPM-UHFFFAOYSA-N |
SMILES | COC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/bestatin-hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4916-Bestatin-hydrochloride-chemical-structure.png |