Brivanib (BMS-540215)
Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
Trivial name | N/A |
Catalog Number | S1084 |
Molecular Formula | C19H19FN4O3 |
CAS# | 649735-46-6 |
Inchi | InChI=1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1 |
Inchi Key | WCWUXEGQKLTGDX-LLVKDONJSA-N |
SMILES | CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OCC(C)O)C |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/Brivanib.html |
Additional Information | https://file.selleck.cn/downloads/struct/Brivanib(BMS-540215)-chemical-structure-s1084.gif |