7α,25-Dihydroxycholesterol
7α,25-Dihydroxycholesterol (7α,25-OHC) is a potent and selective endogenous agonist of the orphan G protein-coupled receptor EBI2 (GPR183). It exhibits high potency in activating EBI2, with an EC50 of 140 pM and a Kd of 450 pM.
Trivial name | 7α,25-OHC |
Catalog Number | E7690 |
Molecular Formula | C23H36N6O5S |
CAS# | 64907-22-8 |
Inchi | InChI=1S/C23H36N6O5S/c1-14-8-10-29(18(12-14)22(31)32)21(30)17(6-4-9-26-23(24)25)28-35(33,34)19-7-3-5-16-11-15(2)13-27-20(16)19/h3,5,7,14-15,17-18,27-28H,4,6,8-13H2,1-2H3,(H,31,32)(H4,24,25,26)/t14-,15 ?,17+,18-/m1/s1 |
Inchi Key | KXNPVXPOPUZYGB-IOVMHBDKSA-N |
SMILES | CC1CCN(C(C1)C(=O)O)C(=O)C(CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/7alpha-25-dihydroxycholesterol.html |
Additional Information | https://file.selleck.cn/downloads/struct/E7690-7a-25-Dihydroxycholesterol-chemical-structure.png |