AS-605240
AS-605240 selectively inhibits PI3Kγ with IC50 of 8 nM, over 30-fold and 7.5-fold more selective for PI3Kγ than PI3Kδ/β and PI3Kα in cell-free assays, respectively.
Trivial name | N/A |
Catalog Number | S1410 |
Molecular Formula | C27H33ClN2O4 |
CAS# | 648450-29-7 |
Inchi | InChI=1S/C27H33ClN2O4/c28-24-7-1-21(2-8-24)27(22-3-9-25(10-4-22)29(13-17-31)14-18-32)23-5-11-26(12-6-23)30(15-19-33)16-20-34/h1-12,27,31-34H,13-20H2 |
Inchi Key | QCXQLSGBOUUVNH-UHFFFAOYSA-N |
SMILES | C1=CC(=CC=C1C(C2=CC=C(C=C2)N(CCO)CCO)C3=CC=C(C=C3)Cl)N(CCO)CCO |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/AS-605240.html |
Additional Information | https://file.selleck.cn/downloads/struct/AS-605240-chemical-structure-S1410.gif |