Meclofenamic acid
Meclofenamic acid (Meclofenamate) is a non-steroidal anti-inflammatory agent. Meclofenamic acid is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker. Meclofenamic acid inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively.
| Trivial name | Meclofenamate |
| Catalog Number | E7490 |
| Molecular Formula | C21H23ClFNO2 |
| CAS# | 644-62-2 |
| Inchi | InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 |
| Inchi Key | LNEPOXFFQSENCJ-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/meclofenamic-acid.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7490-meclofenamic-acid-chemical-structure-tube.png |