Zanthobungeanine, a natural product isolated and purified from the roots of Zanthoxylum nitidum with anti-inflammatory activity, shows the inhibitory action on the development of A549 cell only in high concentration and has no antipersonnel effect on A549 cell, moderate NO production inhibitory activity with an IC50 value of 37.26 mg /L, and obviously inhibitoryactivity to platelet aggregation caused by platelet-activating factor (PAF).