Pazopanib HCl
Pazopanib HCl is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces autophagic Type II cell death.
Trivial name | GW786034 HCl |
Catalog Number | S1035 |
Molecular Formula | C21H23N7O2S.HCl |
CAS# | 635702-64-6 |
Inchi | InChI=1S/C21H23N7O2S.ClH/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16;/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25);1H |
Inchi Key | MQHIQUBXFFAOMK-UHFFFAOYSA-N |
SMILES | CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/Pazopanib-Hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/Pazopanib-chemical-structure-S1035.gif |