Pazopanib HCl

Pazopanib HCl is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces autophagic Type II cell death.

Price Not Available 10mg Pazopanib HCl Supplier Page
Trivial name GW786034 HCl
Catalog Number S1035
Molecular Formula C21H23N7O2S.HCl
CAS# 635702-64-6
Inchi InChI=1S/C21H23N7O2S.ClH/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16;/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25);1H
Inchi Key MQHIQUBXFFAOMK-UHFFFAOYSA-N
SMILES CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
Size 10mg
Supplier Page http://www.selleckchem.com/products/Pazopanib-Hydrochloride.html
Additional Information https://file.selleck.cn/downloads/struct/Pazopanib-chemical-structure-S1035.gif