Pifithrin-α (PFTα) HBr
Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes. Pifithrin-α is also a potent agonist of the aryl hydrocarbon receptor (AhR).
Trivial name | Pifithrin-α hydrobromide |
Catalog Number | S2929 |
Molecular Formula | C29H33NO5 |
CAS# | 63208-82-2 |
Inchi | InChI=1S/C29H33NO5/c1-20-22(12-9-13-24(20)21-10-5-4-6-11-21)19-35-23-16-27(33-2)25(28(17-23)34-3)18-30-15-8-7-14-26(30)29(31)32/h4-6,9-13,16-17,26H,7-8,14-15,18-19H2,1-3H3,(H,31,32)/t26-/m0/s1 |
Inchi Key | ZBOYJODMIAUJHH-SANMLTNESA-N |
SMILES | CC1=C(C=CC=C1C2=CC=CC=C2)COC3=CC(=C(C(=C3)OC)CN4CCCCC4C(=O)O)OC |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/pifithrin-alpha.html |
Additional Information | https://file.selleck.cn/downloads/struct/pifithrin-alpha-chemical-structure-s2929.gif |