AST-487 (NVP-AST487)

AST-487 (NVP-AST487), a N,N’-diphenyl urea,is an ATP competitive inhibitor of Flt3 with ki of 0.12 μM.Besides FLT3, AST487 also inhibits RET,KDR,c-KIT,and c-ABL kinase with IC50 values below 1 μM.

Price Not Available 2mg AST-487 (NVP-AST487) Supplier Page

Trivial name	N/A
Catalog Number	S6662
Molecular Formula	C26H30F3N7O2
CAS#	630124-46-8
Inchi	InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)
Inchi Key	ODPGGGTTYSGTGO-UHFFFAOYSA-N
SMILES	CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)NC3=CC=C(C=C3)OC4=NC=NC(=C4)NC)C(F)(F)F
Size	2mg
Supplier Page	http://www.selleckchem.com/products/ast-487.html
Additional Information	https://file.selleck.cn/downloads/struct/ast-487-chemical-structure-s6662.gif