MK-0812 5mg
MK-0812 is a potent and selective CCR2 antagonist with low nM affinity for CCR2 on human monocytes and low nM in the chemotaxis assay. It has good PK profiles in preclinical species and demonstrated efficacy in animal models.
| Trivial name | MK-0812 5mg |
| Catalog Number | A11127-5 |
| Alternative Name(s) | 1,5-Anhydro-2,3-dideoxy-3-[[(1R,3S)-3-[[7,8-dihydro-3-(trifluoromethyl)-1,6-naphthyridin-6(5H)-yl]carbonyl]-3-(1-methylethyl)cyclopentyl]amino]-4-O-methyl-D-erythro-pentitol |
| Molecular Formula | C24H34F3N3O3 |
| CAS# | 624733-88-6 |
| SMILES | CC(C)[C@@]1(CC[C@H](C1)N[C@H]2CCOC[C@H]2OC)C(=O)N3CCC4=NC=C(C=C4C3)C(F)(F)F |
| Size | 5mg |
| Supplier Page | http://www.adooq.com/mk-0812.html |